SOX4 antibody (N-Term)

Catalog No. ABIN388786

Product Details anti-SOX4 Antibody

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Binding Specificity: AA 86-114, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SOX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the N-terminal region of human SOX4.

Clone: RB18502

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SOX4 antibody (ABIN388786)

Chen, Ruan, Wang, Han, Wang, Lou, Ruan, Qiu, Yang, Zhang: "miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes." in: Journal of cancer research and clinical oncology, Vol. 140, Issue 8, pp. 1295-304, (2014) (PubMed).

Target Details for SOX4

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Alternative Name: SOX4 (SOX4 Products)

Synonyms: EVI16 antibody, AA682046 antibody, Sox-4 antibody, sox4 antibody, wu:fb82f08 antibody, wu:fq41g10 antibody, zgc:65850 antibody, zgc:77392 antibody, SRY-box 4 antibody, SRY box 4 antibody, SRY (sex determining region Y)-box 4 antibody, SRY (sex determining region Y)-box 4a antibody, SOX4 antibody, Sox4 antibody, sox4a antibody

Background: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Molecular Weight: 47263

Gene ID: 6659

NCBI Accession: NP_003098

UniProt: Q06945