VEGFC antibody (AA 248-277)

Catalog No. ABIN388784

Product Details anti-VEGFC Antibody

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Binding Specificity: AA 248-277

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This VEGFC (VEGF3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of human VEGFC (VEGF3).

Clone: RB11715

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for VEGFC

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: VEGFC (VEGF3) (VEGFC Products)

Synonyms: VEGFC antibody, vegf-c antibody, xvegf-c antibody, Flt4-L antibody, VRP antibody, AW228853 antibody, VEGF-C antibody, vascular endothelial growth factor c antibody, vascular endothelial growth factor C antibody, vascular endothelial growth factor C S homeolog antibody, vegfc antibody, VEGFC antibody, vegfc.S antibody, Vegfc antibody

Background: VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Molecular Weight: 46883

Gene ID: 7424

NCBI Accession: NP_005420

UniProt: P49767

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2