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c-MYC antibody (AA 351-380)
MYC
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB11189
unconjugated
Product Details anti-c-MYC Antibody
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Target
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c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Binding Specificity
All epitopes for c-MYC antibodies
AA 351-380
Reactivity
All reactivities for c-MYC antibodies
Human
Host
All hosts for c-MYC antibodies
Rabbit
Clonality
All clonalities for c-MYC antibodies
Polyclonal
Conjugate
All conjugates for c-MYC antibodies
This c-MYC antibody is un-conjugated
Application
All applications for c-MYC antibodies
Western Blotting (WB)
Predicted Reactivity
B, M, Rat, Sh
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MYC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from human MYC.
Clone
RB11189
Isotype
Ig Fraction
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Discover our top product MYC Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for c-MYC
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Target
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Alternative Name
Myc Proto-Oncogene protein (MYC Products )
Synonyms
MRTL antibody, MYCC antibody, bHLHe39 antibody, c-Myc antibody, CMYC antibody, c-myc antibody, C-MYC antibody, LOC100136746 antibody, ARC antibody, B430311C09Rik antibody, MYC antibody, NOP antibody, Nop30 antibody, RNCMYC antibody, mMyc antibody, AU016757 antibody, Myc2 antibody, Niard antibody, Nird antibody, cmyc antibody, zc-myc antibody, c-myc II antibody, myc-B antibody, myc2 antibody, myc1 antibody, CMyc antibody, zgc:55680 antibody, CG10798 antibody, D-Myc antibody, DM antibody, DMYc antibody, Dm antibody, Dmel\CG10798 antibody, Dmyc antibody, EG:BACN5I9.1 antibody, anon-WO03040301.171 antibody, bHLHe57 antibody, c-MYC antibody, d-myc antibody, dMYC antibody, dMyc antibody, dMyc1 antibody, da antibody, dm antibody, dm/dMyc antibody, dm/myc antibody, dmyc antibody, dmyc1 antibody, l(1)G0139 antibody, l(1)G0354 antibody, l(1)G0359 antibody, myc antibody, MYC proto-oncogene, bHLH transcription factor antibody, v-myc myelocytomatosis viral oncogene homolog antibody, nucleolar protein 3 (apoptosis repressor with CARD domain) antibody, myelocytomatosis oncogene antibody, MYC proto-oncogene, bHLH transcription factor a antibody, MYC proto-oncogene, bHLH transcription factor L homeolog antibody, MYC proto-oncogene, bHLH transcription factor S homeolog antibody, v-myc myelocytomatosis viral oncogene homolog (avian) antibody, MYC proto-oncogene, bHLH transcription factor b antibody, CG10798 gene product from transcript CG10798-RB antibody, MYC antibody, LOC100136746 antibody, Nol3 antibody, Myc antibody, myca antibody, myc.L antibody, myc.S antibody, mycb antibody
Background
MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Molecular Weight
48804
Gene ID
4609
NCBI Accession
NP_002458
UniProt
P01106
Pathways
p53 Signaling , Cell Division Cycle , Sensory Perception of Sound , Transition Metal Ion Homeostasis , Mitotic G1-G1/S Phases , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus , Warburg Effect
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