Endoribonuclease Dcr-1 (Dcr-1) (AA 1068-1097) antibody

Catalog No. ABIN388686

Product Details

Target: Endoribonuclease Dcr-1 (Dcr-1)

Binding Specificity: AA 1068-1097

Reactivity: Nematode

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Please inquire

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Dcr-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1068-1097 amino acids of CAEEL Dcr-1.

Clone: RB9834

Isotype: Ig Fraction

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: Endoribonuclease Dcr-1 (Dcr-1)

Alternative Name: Dcr-1 (Dcr-1 Products)

Synonyms: Endoribonuclease dcr-1 antibody, dcr-1 antibody

Background: The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.

Molecular Weight: 218423

Gene ID: 176138

NCBI Accession: NP_498761

UniProt: P34529