NMD3 antibody (C-Term)

Catalog No. ABIN388665

Product Details anti-NMD3 Antibody

Target: NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))

Binding Specificity: AA 410-440, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMD3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NMD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-440 amino acids from the C-terminal region of human NMD3.

Clone: RB9708

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for NMD3

Target: NMD3 (60S Ribosomal Export Protein NMD3 (NMD3))

Alternative Name: NMD3 (NMD3 Products)

Synonyms: RGD1308468 antibody, C87860 antibody, nmd3l antibody, zgc:113103 antibody, NMD3 ribosome export adaptor antibody, NMD3 homolog (S. cerevisiae) antibody, NMD3 ribosome export adaptor L homeolog antibody, Nmd3 antibody, NMD3 antibody, nmd3 antibody, nmd3.L antibody

Background: It has been suggested that NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.

Molecular Weight: 57603

Gene ID: 51068

NCBI Accession: NP_057022

UniProt: Q96D46