RPL23A antibody (C-Term)

Catalog No. ABIN2838385

Product Details anti-RPL23A Antibody

Target: RPL23A (Ribosomal Protein L23A (RPL23A))

Binding Specificity: AA 111-140, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL23A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPL23A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human RPL23A.

Clone: RB9668

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:100. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-RPL23A antibody (ABIN2838385)

Wang, DiMario: "Loss of Drosophila nucleostemin 2 (NS2) blocks nucleolar release of the 60S subunit leading to ribosome stress." in: Chromosoma, Vol. 126, Issue 3, pp. 375-388, (2018) (PubMed).

James, Cindass, Mayer, Terhoeve, Mumphrey, DiMario: "Nucleolar stress in Drosophila melanogaster: RNAi-mediated depletion of Nopp140." in: Nucleus (Austin, Tex.), Vol. 4, Issue 2, pp. 123-33, (2013) (PubMed).

Target Details for RPL23A

Target: RPL23A (Ribosomal Protein L23A (RPL23A))

Alternative Name: RPL23A (RPL23A Products)

Synonyms: L23A antibody, MDA20 antibody, BC029892 antibody, RPL23AY antibody, ribosomal protein L23a antibody, ribosomal protein L23A antibody, RPL23A antibody, Rpl23a antibody

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL23A is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located in its third, first, second, and fourth introns, respectively.

Molecular Weight: 17695

Gene ID: 6147

NCBI Accession: NP_000975

UniProt: P62750