Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This Bmp3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human Bmp3.
BMP-3A antibody, PBMP3 antibody, 9130206H07 antibody, 9530029I04Rik antibody, BMP3 antibody, BMP-3 antibody, wu:fk96e01 antibody, zgc:153939 antibody, xBMP-3 antibody, bone morphogenetic protein 3 antibody, bone morphogenetic protein 3 L homeolog antibody, BMP3 antibody, Bmp3 antibody, bmp3 antibody, bmp3.L antibody
Background
The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.