Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This TXNL1 (TRP32/TrxL) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-289 amino acids from the C-terminal region of human TXNL1 (TRP32/TrxL).
TRP32 antibody, TXL-1 antibody, TXNL antibody, Txl antibody, 32kDa antibody, Txnl antibody, zgc:55368 antibody, MGC81675 antibody, txnl1 antibody, MGC89177 antibody, TXNL1 antibody, thioredoxin like 1 antibody, thioredoxin-like 1 antibody, thioredoxin like 1 S homeolog antibody, thioredoxin-related protein antibody, thioredoxin-like I protein Txl1 antibody, TXNL1 antibody, Txnl1 antibody, txnl1 antibody, txnl1.S antibody, Deipr_2190 antibody, txl1 antibody
Background
Thioredoxins are a group of small redox active proteins possessing a conserved active site sequence. TrxL (Thioredoxin like protein 1) has 2 distinct domains: an N terminal domain, which is 43 % identical to human TXN, and a C terminal domain, which shows no homology to other proteins in the sequence databases. The active site sequence, located within the N terminal domain, is that of a thioredoxin like protein, compared to the active site sequence of TXN, it has a single amino acid substitution. Unlike other thioredoxin like proteins, TrxL does not serve as a substrate for thioredoxin reductase in an insulin assay.