APEH antibody (N-Term)

Catalog No. ABIN388069

Product Details anti-APEH Antibody

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Binding Specificity: AA 174-204, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APEH antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This APEH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-204 amino acids from the N-terminal region of human APEH.

Clone: RB18348

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for APEH

Target: APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Alternative Name: APEH (APEH Products)

Synonyms: AARE antibody, ACPH antibody, APH antibody, D3F15S2 antibody, D3S48E antibody, DNF15S2 antibody, OPH antibody, AAP antibody, cb5 antibody, sb:cb5 antibody, wu:fi37d02 antibody, acylaminoacyl-peptide hydrolase antibody, acylpeptide hydrolase antibody, APEH antibody, Apeh antibody, apeh antibody

Background: APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.

Molecular Weight: 81225

Gene ID: 327

NCBI Accession: NP_001631

UniProt: P13798