SENP5 antibody (C-Term)

Catalog No. ABIN388050

Product Details anti-SENP5 Antibody

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Binding Specificity: AA 524-555, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pr, M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 524-555 amino acids from the C-terminal region of human SENP5.

Clone: RB0660

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SENP5 antibody (ABIN388050)

Cheng, Guo, Gong, Ding, Yu: "Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 2009-14, (2015) (PubMed).

Target Details for SENP5

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Alternative Name: SENP5 (SENP5 Products)

Synonyms: 6230429P13Rik antibody, A730063F07Rik antibody, AI851888 antibody, BB189556 antibody, SMT3IP3 antibody, SENP5 antibody, Senp5 antibody, senp5 antibody, SUMO1/sentrin specific peptidase 5 antibody, SUMO/sentrin specific peptidase 5 antibody, SUMO1/sentrin specific peptidase 5 L homeolog antibody, SENP5 antibody, Senp5 antibody, senp5 antibody, senp5.L antibody

Background: SENP5 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its conjugatable mature form and deconjugation of SUMO2 and SUMO3 from targeted substrates. This protein has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. SENP5 is required for cell division.

Molecular Weight: 86693

Gene ID: 205564

NCBI Accession: NP_689912

UniProt: Q96HI0