This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ELP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-44 amino acids from the N-terminal region of human ELP3.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Barton, Braet, Marc, Overall, Gardiner: "ELP3 localises to mitochondria and actin-rich domains at edges of HeLa cells." in: Neuroscience letters, Vol. 455, Issue 1, pp. 60-4, (2009) (PubMed).
Target
ELP3/KAT9 (ELP3)
(Elongator complex protein 3 (ELP3))
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.