PRMT7 antibody (C-Term)

Catalog No. ABIN387847

Product Details anti-PRMT7 Antibody

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Binding Specificity: AA 660-692, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PRMT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 660-692 amino acids from the C-terminal region of human PRMT7.

Clone: RB7773-RB7774

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Alternative Name: PRMT7 (PRMT7 Products)

Background: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Molecular Weight: 78459

Gene ID: 54496

NCBI Accession: NP_001171753, NP_061896

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization