PRMT3 antibody (C-Term)
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- Target See all PRMT3 Antibodies
- PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))
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Binding Specificity
- AA 460-491, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRMT3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- M
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This PRMT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-491 amino acids from the C-terminal region of human PRMT3.
- Clone
- RB0115
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PRMT3 Primary Antibody
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))
- Alternative Name
- PRMT3 (PRMT3 Products)
- Background
- Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
- Molecular Weight
- 59903
- Gene ID
- 10196
- NCBI Accession
- NP_005779
- UniProt
- O60678
- Pathways
- Protein targeting to Nucleus
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