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CD11b antibody

ITGAM Reactivity: Rat IHC, IHC (fro) Host: Mouse Monoclonal OX-42 unconjugated
Catalog No. ABIN380068
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 258
    • 163
    • 64
    • 34
    • 20
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    • 1
    Rat
    Host
    • 141
    • 105
    • 103
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    • 1
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    Mouse
    Clonality
    • 254
    • 96
    • 1
    Monoclonal
    Conjugate
    • 116
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    • 21
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    • 2
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    This CD11b antibody is un-conjugated
    Application
    • 265
    • 84
    • 78
    • 78
    • 56
    • 44
    • 36
    • 22
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    Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    CD11b/c. OX-42 recognizes three major polypeptides of 160  kDa, 103  kDa and 95  kDa and a minor 133  kDa protein under non-reducing conditions. Under reducing conditions two major peptides of 163  kDa and 100  kDa and a minor 135  kDa peptide are detected. Antigen distribution: Isolated cells: OX-42 shows a similar reaction pattern to OX-41 on various isolated cells but stains bronchial lavage cells to a lesser degree. OX-42 inhibits complement mediated rosettes. Tissue sections: OX-42 is a most suitable marker for the identification of microglial cells and Kupffer cells. It also stains dendritic cells strongly. Only a subpopulation of alveolar macrophages is recognised. Specificity: Rat: granulocytes, macrophages, microglial cells. Other species: not tested
    Purification
    Purified
    Immunogen
    Peritoneal macrophages
    Clone
    OX-42
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    Approved: IHC, IHC-Fr (1:100 - 1:200)
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS  pH 7.2, 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b + C (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
    Gene ID
    3684
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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