CD11b antibody
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD11b antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- CD11b/c. OX-42 recognizes three major polypeptides of 160 kDa, 103 kDa and 95 kDa and a minor 133 kDa protein under non-reducing conditions. Under reducing conditions two major peptides of 163 kDa and 100 kDa and a minor 135 kDa peptide are detected. Antigen distribution: Isolated cells: OX-42 shows a similar reaction pattern to OX-41 on various isolated cells but stains bronchial lavage cells to a lesser degree. OX-42 inhibits complement mediated rosettes. Tissue sections: OX-42 is a most suitable marker for the identification of microglial cells and Kupffer cells. It also stains dendritic cells strongly. Only a subpopulation of alveolar macrophages is recognised. Specificity: Rat: granulocytes, macrophages, microglial cells. Other species: not tested
- Purification
- Purified
- Immunogen
- Peritoneal macrophages
- Clone
- OX-42
- Top Product
- Discover our top product ITGAM Primary Antibody
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- Application Notes
- Approved: IHC, IHC-Fr (1:100 - 1:200)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS pH 7.2, 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C.
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- CD11b + C (ITGAM Products)
- Synonyms
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- Background
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Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain - Gene ID
- 3684
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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