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ITGA2 antibody

ITGA2 Reactivity: Human FACS Host: Mouse Monoclonal HAS-4 unconjugated
Catalog No. ABIN376997
  • Target See all ITGA2 Antibodies
    ITGA2 (Integrin alpha 2 (ITGA2))
    Reactivity
    • 123
    • 60
    • 22
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 79
    • 43
    • 19
    • 5
    • 5
    Mouse
    Clonality
    • 81
    • 73
    Monoclonal
    Conjugate
    • 62
    • 24
    • 17
    • 14
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA2 antibody is un-conjugated
    Application
    • 66
    • 64
    • 42
    • 38
    • 14
    • 12
    • 11
    • 11
    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Specificity
    Human CD49b, Mr 160 kDa
    Characteristics
    Mouse Anti-Human CD49b-UNLB
    Purification
    Purified
    Immunogen
    Human keratinocytes
    Clone
    HAS-4
    Isotype
    IgG2a
    Top Product
    Discover our top product ITGA2 Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Sample Volume
    1 mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Preservative
    Without preservative
    Handling Advice
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    ITGA2 (Integrin alpha 2 (ITGA2))
    Alternative Name
    CD49b (ITGA2 Products)
    Synonyms
    BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
    Background
    CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin α 2 chain. CD49b associates noncovalently with CD29, the integrin β 1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg ++ - dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.
    Pathways
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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