ITGA2 antibody (PE)
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- Target See all ITGA2 Antibodies
- ITGA2 (Integrin alpha 2 (ITGA2))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ITGA2 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- Human CD49b, Mr 160 kDa
- Characteristics
- Mouse Anti-Human CD49b-PE
- Purification
- Purified
- Immunogen
- Human keratinocytes
- Clone
- HAS-4
- Isotype
- IgG2a
- Top Product
- Discover our top product ITGA2 Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Restrictions
- For Research Use only
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- Buffer
- 100 tests in 1.0 mL of PBS/Sodium azide and a stabilizing agent
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Storage
- 4 °C
- Storage Comment
- Store at 2-8°C
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- Target
- ITGA2 (Integrin alpha 2 (ITGA2))
- Alternative Name
- CD49b (ITGA2 Products)
- Synonyms
- BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
- Background
- CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin α 2 chain. CD49b associates noncovalently with CD29, the integrin β 1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg ++ - dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.
- Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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