This antibody is expected to recognise both reported isoforms (NP_000925.2, NP_001159393.1). Reported variants represent identical protein (NP_000925.2, NP_001159392.1).
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_000925.2, NP_001159393.1. Genename: SERPINF2
SERPINF2
Reactivity: Human, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: 1/16000. Western Blot: 0.3 - 1 μg/mL. Immunohistochemistry on paraffin sections: 3 - 5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
A2AP antibody, AAP antibody, ALPHA-2-PI antibody, API antibody, PLI antibody, serpin antibody, AI747498 antibody, Pli antibody, Serpimf2 antibody, serpinf2 antibody, serpinf2l antibody, wu:fd57d08 antibody, Dmrs91 antibody, Pedf antibody, serpin family F member 2 antibody, serpin family F member 1 antibody, serine (or cysteine) peptidase inhibitor, clade F, member 2 antibody, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a antibody, SERPINF2 antibody, Serpinf2 antibody, SERPINF1 antibody, serpinf2a antibody, Serpinf1 antibody
Background
Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. The protein has a major role in regulating the blood clotting pathway. Mutations result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: AAP, Alpha-2-AP, Alpha-2-PI, Alpha-2-plasmin inhibitor, PLI, Serpin F2