TACR1 antibody (Internal Region)
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- Target See all TACR1 Antibodies
- TACR1 (Tachykinin Receptor 1 (TACR1))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Rat, Mouse, Dog
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This TACR1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- C-EIPGDSSDRY HEQ
- Specificity
- This antibody detects Tachykinin receptor 1 (TACR1).
- Cross-Reactivity (Details)
- Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human
- Purification
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- Immunogen
- Peptide from the internal region of the protein sequence according to NP_001049.1, NP_056542.1. Genename: TACR1
- Top Product
- Discover our top product TACR1 Primary Antibody
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- Application Notes
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Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 36 kDa band observed in Human Testis lysates (calculatedMW of 35.6 kDa according to NP_056542.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- Target
- TACR1 (Tachykinin Receptor 1 (TACR1))
- Abstract
- TACR1 Products
- Background
- The neurokinin-1 (NK1) receptor is a G-protein-coupled receptor characterized by seven transmembrane helices which preferentially binds the neuropeptide substance P. NK1 receptor (also known as the Substance P Receptor) plays a key role in pain and inflammation. Studies also implicate NK1 receptor in depression and the growth of brain tumors. The NK1 receptor has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R
- Gene ID
- 6869, 9606
- UniProt
- P25103
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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