Melanoma gp100 antibody (C-Term)
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- Target See all Melanoma gp100 (PMEL) Antibodies
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Melanoma gp100 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody recognizes Silver homologue / Pmel17.
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography
- Immunogen
- Peptide with sequence CPIGENSPLLSGQQ, from the C Terminus of the protein sequence according to NP_008859.1
- Top Product
- Discover our top product PMEL Primary Antibody
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- Application Notes
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Alternative Name
- Melanoma Gp100 (PMEL Products)
- Synonyms
- D12S53E antibody, ME20 antibody, ME20-M antibody, ME20M antibody, P1 antibody, P100 antibody, PMEL17 antibody, SI antibody, SIL antibody, SILV antibody, gp100 antibody, D10H12S53E antibody, D12S53Eh antibody, Pmel17 antibody, Si antibody, Silv antibody, gp87 antibody, RPE1 antibody, MMP115 antibody, silverb antibody, silver antibody, cb397 antibody, fdv antibody, pmel17 antibody, sb:cb397 antibody, silva antibody, wu:fc11g11 antibody, wu:fj24g11 antibody, zgc:136622 antibody, premelanosome protein antibody, premelanosome protein b antibody, premelanosome protein a antibody, PMEL antibody, Pmel antibody, pmelb antibody, pmela antibody
- Background
- Melanoma gp100, a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes. It is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.Synonyms: D12S53E, ME20-M, Melanocyte lineage-specific antigen GP100, Melanocyte protein Pmel 17, Melanoma-associated ME20 antigen, PMEL17, SILV, Silver locus protein homolog
- Molecular Weight
- 70.3kDa (NP_008859.1).
- Gene ID
- 6490
- NCBI Accession
- NP_001186982
- UniProt
- P40967
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