LDLRAP1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: Limit dilution 1: 16000. Western blot: 1-3 μg/mL. Approx 40-45 kDa band observed in Human Liver lysate (predictedMW of 35 kDa according to NP_056442.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Target
LDLRAP1
(Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
ARH antibody, ARH1 antibody, ARH2 antibody, FHCB1 antibody, FHCB2 antibody, AA691260 antibody, Arh antibody, Arh1 antibody, RGD1563417 antibody, arh antibody, arh1 antibody, arh2 antibody, fhcb1 antibody, fhcb2 antibody, xptb antibody, LDLRAP1 antibody, ldlrap1 antibody, sb:cb50 antibody, zgc:56121 antibody, zgc:158745 antibody, low density lipoprotein receptor adaptor protein 1 antibody, low density lipoprotein receptor adaptor protein 1 L homeolog antibody, low density lipoprotein receptor adaptor protein 1 S homeolog antibody, low density lipoprotein receptor adaptor protein 1a antibody, low density lipoprotein receptor adaptor protein 1b antibody, LDLRAP1 antibody, Ldlrap1 antibody, ldlrap1 antibody, ldlrap1.L antibody, ldlrap1.S antibody, ldlrap1a antibody, ldlrap1b antibody
Background
ARH is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.Synonyms: ARH, Autosomal recessive hypercholesterolemia protein, LDLRAP1, Low density lipoprotein receptor adapter protein 1