RAPSN antibody (C-Term)

Catalog No. ABIN372886

Product Details anti-RAPSN Antibody

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPSN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Receptor-associated Protein Of The Synapse, 43 kDa (RAPSN).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 10 - 20 μg/mL. Western blot: 1 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.01 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for RAPSN

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Alternative Name: RAPSN / RNF205 (RAPSN Products)

Background: Nicotinic acetylcholine receptors (AChRs) are organized into high-density postsynaptic clusters at the motor endplate that are critical for efficient synaptic transmission. The organization of AChRs is carried out by the 43 kDa cytoplasmic protein rapsyn. Studies have indicated that mutations which impair the activity of rapsyn can lead to the formation of congenital myasthenic syndrome (CMS). CMS is characterized by poor development of the postsynaptic region.Synonyms: 43 kDa postsynaptic protein, 43 kDa receptor-associated protein of the synapse, Acetylcholine receptor-associated 43 kDa protein, RAPsyn, RING finger protein 205

Gene ID: 5913

NCBI Accession: NP_005046

UniProt: Q13702