Tamalin/GRASP antibody (C-Term)

Catalog No. ABIN372659

Product Details anti-Tamalin/GRASP Antibody

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Binding Specificity: C-Term

Reactivity: Mouse, Rat, Human, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tamalin/GRASP antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody is specific for the ~95k GRASP protein.

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Canine, Human and Mouse.
Species reactivity (tested):Rat.

Purification: Affinity Chromatography.

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of rat GRASP, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at-20 °C.

Target Details for Tamalin/GRASP

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Alternative Name: GRASP (GRASP Products)

Synonyms: GRASP antibody, tamalin antibody, TAMALIN antibody, general receptor for phosphoinositides 1 associated scaffold protein antibody, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein antibody, GRASP antibody, grasp antibody, Grasp antibody

Background: PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).Synonyms: GRP1-associated scaffold protein, General receptor for phosphoinositides 1-associated scaffold protein

Gene ID: 192254

NCBI Accession: NP_620249

UniProt: Q8R4T5