MYO5B antibody (N-Term)

Catalog No. ABIN372473

Product Details anti-MYO5B Antibody

Target: MYO5B (Myosin VB (MYO5B))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO5B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Myosin VB (MYO5B).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide (KLH conjugated) corresponding to N-terminal residues of human Myosin-5B (Myosin Vb).

Isotype: IgG

Application Details

Application Notes: ELISA: 1 μg/mL. Western blot: 1 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MYO5B

Target: MYO5B (Myosin VB (MYO5B))

Alternative Name: MYO5B (MYO5B Products)

Background: MYO5B interacts with RAB11FIP2. MYO5B has a role in in glutamate receptor GluR1 trafficking. MYO5B functions in traffic between peripheral and pericentrosomal compartments. The protein contains 1 dilute domain and 6 IQ domains. It also contains 1 myosin head-like domain. The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.Synonyms: KIAA1119, Myosin-Vb

Molecular Weight: 214 kDa.

Gene ID: 4645

NCBI Accession: NP_001073936

UniProt: Q9ULV0