Derlin-3 antibody (N-Term)

Catalog No. ABIN372297

Product Details anti-Derlin-3 Antibody

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Derlin-3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Derlin-3/DERL3 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to N-terminal residues of Human DERL3 (Derlin-3).

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL. ELISA: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Derlin-3

Target: Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))

Alternative Name: Derlin-3 (DERL3 Products)

Synonyms: 1810006I20Rik antibody, 1810063P04Rik antibody, IZP6 antibody, derlin-3 antibody, zgc:63991 antibody, C22orf14 antibody, LLN2 antibody, derlin 3 antibody, Der1-like domain family, member 3 antibody, DERL3 antibody, Derl3 antibody, derl3 antibody

Background: DERL3 (Derlin-3) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclearSynonyms: C22orf14, DER3, DERL3, Degradation in endoplasmic reticulum protein 3, Der1-like protein 3, LLN2

Molecular Weight: 27 kDa.

Gene ID: 91319

NCBI Accession: NP_001002862

UniProt: Q96Q80

Pathways: ER-Nucleus Signaling