PPP1R1A antibody (AA 50-100)

Catalog No. ABIN372270

Product Details anti-PPP1R1A Antibody

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Binding Specificity: AA 50-100

Reactivity: Human, Rat, Mouse, Dog, Monkey, Cow, Xenopus laevis, Chimpanzee, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes Protein Phosphatase-1 Inhibitor (PPP1R1A).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chimpanzee, Dog (Canine), Xenopus, Horse, Monkey, Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 50-100 of human IPP-1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PPP1R1A

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Alternative Name: PPP1R1A (PPP1R1A Products)

Synonyms: I1 antibody, IPP1 antibody, 0610038N18Rik antibody, I-1 antibody, pil antibody, IPP-1 antibody, protein phosphatase 1 regulatory inhibitor subunit 1A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 1A antibody, protein phosphatase 1 regulatory inhibitor subunit 1A L homeolog antibody, PPP1R1A antibody, Ppp1r1a antibody, ppp1r1a.L antibody

Background: Protein phosphotase inhibitor 1 (IPP1) may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase IPP1 activity in many tissues. IPP1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, IPP1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.Synonyms: IPP-1, IPP1, Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1

Molecular Weight: 19 kDa

Gene ID: 5502

NCBI Accession: NP_006732

UniProt: Q13522

Pathways: Cellular Glucan Metabolic Process