H2-Q7 antibody

Catalog No. ABIN371161

Product Details anti-H2-Q7 Antibody

Target: H2-Q7 (Histocompatibility 2, Q Region Locus 7 (H2-Q7))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This H2-Q7 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Specificity: This antibody recognises Qa-2 alloantigen. It reacts with a Qa-2-determined alloantigen.

Characteristics: Synonyms: H2Qa2

Purification: Purified

Immunogen: C3H. SW mouse skin graft and splenocytes. (Ref. 1)

Clone: 695H1-9-9

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. Complement-mediated cytotoxicityModulation of Qa-2 expression from peripheral T lymphocytesa. (Ref.2)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for H2-Q7

Target: H2-Q7 (Histocompatibility 2, Q Region Locus 7 (H2-Q7))

Alternative Name: QA-2 Antigen (H2-Q7 Products)

Synonyms: H-2Q7 antibody, Ped antibody, Q9 antibody, Qa-2 antibody, Qa-7 antibody, Qa7 antibody, histocompatibility 2, Q region locus 7 antibody, H2-Q7 antibody

Background: Qa antigens are 'non classical' MHC class I molecules of mice. Qa2 is present on restricted functional lymphocyte subpopulations. The protein product of the preimplantation embryo development (Ped) gene, Qa2 influences the rate of embryonic cleavage during the preimplantation stages of development.Synonyms: H2Qa2

Gene ID: 100044019

UniProt: P14429