Nth Endonuclease III-Like 1 (NTHL1) antibody

Catalog No. ABIN363381

Product Details

Target: Nth Endonuclease III-Like 1 (NTHL1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Reacts with NTH1 from human, mouse and rat

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Immunogen sequence has 93 % identity with bovine proteins.

Purification: Antigen affinity purified

Immunogen: Peptide derived from the human NTH1 conjugated to KLH

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/500 - ICC/IF: 1/800

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details

Target: Nth Endonuclease III-Like 1 (NTHL1)

Alternative Name: NTH1 (NTHL1 Products)

Synonyms: psmc3 antibody, psmc3-a antibody, nth-like DNA glycosylase 1 S homeolog antibody, nthl1.S antibody

Background: NTH1 (endonuclease III-like protein 1 or NTHL1) has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.

Gene ID: 4913