Neurofilament (Light Chain) antibody
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- Target
- Neurofilament (Light Chain)
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
- Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting (WB)
- Specificity
- Reacts with the light neurofilament subunit (~68 kDa)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
- Cross-Reactivity (Details)
- Cross reacts with NF-L from human, cow, pig, mouse, rat and all other mammals. This antibody also recognizes avian NF-L.
- Purification
- Antiserum
- Immunogen
- Native NF-L purified from pig spinal cord
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anti-Neurofilament (Light Chain) antibody
Reactivity: Human, Rat IHC (p), IF Host: Mouse Monoclonal MSI27-1 unconjugated
anti-Neurofilament (Light Chain) antibodyReactivity: Human, Rat IHC (p), IF Host: Mouse Monoclonal MSI27-1 unconjugated
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:20000 ICC/ IF1:500-1:5000 IHC-P1:5000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- -20 °C/-80 °C
- Storage Comment
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- Target
- Neurofilament (Light Chain)
- Alternative Name
- Neurofilament light chain
- Background
- Belongs to the intermediate filament family. Interacts with RGNEF and with TRIM2. Defects in NEFL are the cause of Charcot-Marie-Tooth disease type 1F.
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