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HDAC4/HDAC5/HDAC9 antibody (AA 244-248)

Reactivity: Human, Mouse WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN363088
  • Target See all HDAC4/HDAC5/HDAC9 products
    HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)
    Binding Specificity
    • 10
    • 10
    • 9
    • 2
    • 1
    • 1
    AA 244-248
    Reactivity
    • 20
    • 10
    • 1
    Human, Mouse
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HDAC4/HDAC5/HDAC9 antibody is un-conjugated
    Application
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Specificity
    The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody detects endogenous levels of total HDAC4/HDAC5/HDAC9 protein.
    Immunogen
    Peptide sequence around AA 244-248, 257-261, 218-222 (T-A-S-E-P) derived from Human HDAC4, HDAC5, HDAC9. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotype
    IgG
  • Application Notes
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)
    Alternative Name
    HDAC4/HDAC5/HDAC9 (HDAC4/HDAC5/HDAC9 Products)
    Synonyms
    AHO3 antibody, BDMR antibody, HA6116 antibody, HD4 antibody, HDAC-4 antibody, HDAC-A antibody, HDACA antibody, histone deacetylase 4 antibody, HDAC4 antibody
    Background
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
    Molecular Weight
    124 kDa
    NCBI Accession
    NP_055522, NP_001015
    UniProt
    Q9UKV0
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