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STAT5A antibody (AA 778-782)
STAT5A
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-STAT5A Antibody
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Target
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STAT5A
(Signal Transducer and Activator of Transcription 5A (STAT5A))
Binding Specificity
All epitopes for STAT5A antibodies
AA 778-782
Reactivity
All reactivities for STAT5A antibodies
Human, Mouse, Rat
Host
All hosts for STAT5A antibodies
Rabbit
Clonality
All clonalities for STAT5A antibodies
Polyclonal
Conjugate
All conjugates for STAT5A antibodies
This STAT5A antibody is un-conjugated
Application
All applications for STAT5A antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
The antibody detects endogenous level of total STAT5A protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 778-782 (R-L-S-P-P) derived from Human STAT5A. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
References for anti-STAT5A antibody (ABIN362574)
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Cheng, Wang, Xia, Yan, Tang, Chen, Zhang, Liu, Kong, Sjöberg, Folco, Libby, Liao, Shi : "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation. " in: EMBO molecular medicine , Vol. 4 , Issue 10 , pp. 1112-25 , (2012 ) (PubMed ).
Target Details for STAT5A
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Target
STAT5A
(Signal Transducer and Activator of Transcription 5A (STAT5A))
Alternative Name
STAT5A (STAT5A Products )
Synonyms
MGF antibody, STAT5 antibody, AA959963 antibody, Stat5 antibody, STAT5A/MGF antibody, STATA5 antibody, STAT5A antibody, stat5 antibody, stat5b antibody, signal transducer and activator of transcription 5A antibody, signal transducer and activator of transcription 5a antibody, STAT5A antibody, Stat5a antibody, stat5a antibody, LOC100348518 antibody, LOC100716811 antibody
Background
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Molecular Weight
90 kDa
NCBI Accession
NP_003143
UniProt
P42229
Pathways
JAK-STAT Signaling , RTK Signaling , Response to Growth Hormone Stimulus , C21-Steroid Hormone Metabolic Process , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , CXCR4-mediated Signaling Events , Activated T Cell Proliferation
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