The antibody detects endogenous level of total Myc protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 371-375 (K-R-S-F-F) derived from Human Myc. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
MYC
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
7-00E-10
unconjugated
Application Notes
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Giugliano, Ruff, Braunwald, Murphy, Wiviott, Halperin, Waldo, Ezekowitz, Weitz, Špinar, Ruzyllo, Ruda, Koretsune, Betcher, Shi, Grip, Patel, Patel, Hanyok, Mercuri, Antman: "Edoxaban versus warfarin in patients with atrial fibrillation." in: The New England journal of medicine, Vol. 369, Issue 22, pp. 2093-104, (2013) (PubMed).
Liu, Ma, Lee: "NMDA receptor signaling mediates the expression of protein inhibitor of activated STAT1 (PIAS1) in rat hippocampus." in: Neuropharmacology, Vol. 65, pp. 101-13, (2012) (PubMed).
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.