Cofilin antibody (pTyr139)
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- Target See all Cofilin (CFL1) Antibodies
- Cofilin (CFL1) (Cofilin 1 (CFL1))
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Binding Specificity
- pTyr139
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cofilin antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Specificity
- The antibody detects endogenous level of cofilin1 only when phosphorylated at tyrosine 139.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogen
- Peptide sequence around phosphorylation site of pTyr139 (N-C-Y (p) -E-E) derived from Human cofilin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Isotype
- IgG
- Top Product
- Discover our top product CFL1 Primary Antibody
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- Application Notes
- Immunohistochemistry: 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- Cofilin (CFL1) (Cofilin 1 (CFL1))
- Alternative Name
- cofilin1 (CFL1 Products)
- Synonyms
- cfl1 antibody, xac1 antibody, xac2 antibody, cfl antibody, cb86 antibody, sb:cb86 antibody, zgc:56501 antibody, wu:fb18a04 antibody, wu:fk77b03 antibody, 12/8 antibody, ADF antibody, ADF/cofilin antibody, Adf antibody, CG4254 antibody, Cadf antibody, D-cof antibody, D61 antibody, Dmel\\CG4254 antibody, T8 antibody, Tsr antibody, cofilin antibody, cofilin/ADF antibody, cofilin/actin depolymerizing factor homolog antibody, l(2)03101 antibody, l(2)k03101 antibody, l(2)k05633 antibody, l(2)k13409 antibody, ntf antibody, CFL antibody, AA959946 antibody, Cof antibody, CFL1 antibody, cofilin 1 (non-muscle) L homeolog antibody, cofilin 1 (non-muscle) antibody, cofilin 1 (non-muscle), like antibody, cofilin 1 antibody, twinstar antibody, cofilin antibody, cofilin 1, non-muscle antibody, Contrafreeloading antibody, cfl1.L antibody, cfl1 antibody, cfl1l antibody, CFL1 antibody, tsr antibody, COF1 antibody, TSTA_042790 antibody, Cfl1 antibody, CFL antibody
- Background
- Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
- Molecular Weight
- 19 kDa
- NCBI Accession
- NP_005498
- UniProt
- P23528
- Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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