DBH antibody (N-Term)

Catalog No. ABIN361428

Product Details anti-DBH Antibody

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Binding Specificity: N-Term

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This DBH antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Specific for the ~75k DBH protein in Western blots.

Cross-Reactivity: Human, Non-Human Primate

Purification: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Target Details for DBH

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Alternative Name: DBH (DBH Products)

Synonyms: CG1543 antibody, DBH antibody, Dbh antibody, Dmel\\CG1543 antibody, T beta h antibody, TBH antibody, TBetaH antibody, TBetah antibody, TBh antibody, TbetaH antibody, TbetaM antibody, Tbetah antibody, tbh antibody, DBM antibody, DOPBHY antibody, Tbh antibody, dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody, Tyramine beta hydroxylase antibody, MOXD1 homolog 2 antibody, dopamine beta hydroxylase antibody, dopamine beta-hydroxylase antibody, dbh antibody, Tbh antibody, LOC5574699 antibody, CpipJ_CPIJ004736 antibody, CpipJ_CPIJ004737 antibody, CpipJ_CPIJ014202 antibody, CpipJ_CPIJ016745 antibody, CpipJ_CPIJ019034 antibody, DBH antibody, Dbh antibody, LOC101110668 antibody

Background: DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001). Anti-Dopamine ß-Hydroxylase Western blot of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein.

Molecular Weight: '75 kDa

Gene ID: 1621

UniProt: P09172

Pathways: Carbohydrate Homeostasis