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DBH antibody (C-Term)

DBH Reactivity: Human WB Host: Sheep Polyclonal unconjugated
Catalog No. ABIN361427
  • Target See all DBH Antibodies
    DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))
    Binding Specificity
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 54
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 39
    • 12
    • 5
    • 1
    Sheep
    Clonality
    • 53
    • 4
    Polyclonal
    Conjugate
    • 44
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DBH antibody is un-conjugated
    Application
    • 47
    • 23
    • 20
    • 12
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Specific for the ~75k DBH protein in Western blots.
    Cross-Reactivity
    Human, Mouse (Murine), Non-Human Primate
    Purification
    Antigen Affinity Purified from Pooled Serum
    Immunogen
    Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
    Top Product
    Discover our top product DBH Primary Antibody
  • Application Notes
    Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    Storage
    -20 °C
  • Target
    DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))
    Alternative Name
    DBH (DBH Products)
    Background
    DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001). Anti-Dopamine ß-Hydroxylase Western blot of human adrenal medulla lysate showing specific immunolabeling of the ~75k DBH protein.
    Molecular Weight
    '75 kDa
    Gene ID
    1621
    UniProt
    P09172
    Pathways
    Carbohydrate Homeostasis
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