RPH3A antibody (C-Term)

Catalog No. ABIN361408

Product Details anti-RPH3A Antibody

Target: RPH3A (Rabphilin 3A (RPH3A))

Binding Specificity: C-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPH3A antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Specific for the ~82k rabphilin 3A protein.

Cross-Reactivity: Rat (Rattus)

Predicted Reactivity: mouse, human, bovine, canine and non-human primate

Purification: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Target Details for RPH3A

Target: RPH3A (Rabphilin 3A (RPH3A))

Alternative Name: RPH3A (RPH3A Products)

Background: Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington?s disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001). Anti- Rabphilin 3A Western blot of rat cortex lysate showing specific immunolabeling of the ~82k rabphilin 3A.

Molecular Weight: '82 kDa

Gene ID: 171039

UniProt: P47709

Pathways: Synaptic Vesicle Exocytosis