OLIG1 antibody

Catalog No. ABIN361358

Product Details anti-OLIG1 Antibody

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OLIG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Specificity: Specific for the ~27 kDa Olig1 protein in Western blots. The antibody also works well for immunohistochemistry, immunocytochemistry and immunoprecipitation.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Protein A purified

Immunogen: Recombinant mouse Olig1

Application Details

Application Notes: Recommended Dilution: WB: 1:3,000 IHC & ICC: 1:1,000 IP: 1:50 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 100 mM Glycine, 200 mM Tris,  pH 8.0

Storage: -20 °C

Target Details for OLIG1

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Alternative Name: OLIG1 (OLIG1 Products)

Synonyms: OLIG1 antibody, BHLHB6 antibody, BHLHE21 antibody, AI836478 antibody, AW494459 antibody, Bhlhb6 antibody, Olg-1 antibody, Oligo1 antibody, bHLHe21 antibody, Olg1 antibody, oligodendrocyte transcription factor 1 antibody, OLIG1 antibody, Olig1 antibody

Background: Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004). Anti-Olig1 Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~ 27k Olig1 protein.

Molecular Weight: '27 kDa

Gene ID: 50914

UniProt: Q9JKN5