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NEFM antibody (C-Term)

NEFM Reactivity: Rat WB, IF Host: Chicken Polyclonal unconjugated
Catalog No. ABIN361355
  • Target See all NEFM Antibodies
    NEFM (Neurofilament Triplet M Protein (NEFM))
    Binding Specificity
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 61
    • 43
    • 35
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Rat
    Host
    • 41
    • 23
    • 10
    • 1
    Chicken
    Clonality
    • 43
    • 32
    Polyclonal
    Conjugate
    • 47
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFM antibody is un-conjugated
    Application
    • 61
    • 22
    • 21
    • 17
    • 14
    • 13
    • 13
    • 11
    • 10
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    Specific for the ~145k Neurofilament M protein.
    Cross-Reactivity
    Chicken, Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
    Purification
    Total IgY fraction
    Immunogen
    Preparation containing the extreme C-terminus expressed in and purified from E. Coli
    Top Product
    Discover our top product NEFM Primary Antibody
  • Application Notes
    Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    total IgY fraction in PBS + 10 mM Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).

  • Target
    NEFM (Neurofilament Triplet M Protein (NEFM))
    Alternative Name
    NEFM (NEFM Products)
    Background
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.
    Molecular Weight
    '145 kDa
    Gene ID
    24588
    UniProt
    P12839
    Pathways
    Brown Fat Cell Differentiation
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