IL20RA antibody (Extracellular Domain)

Catalog No. ABIN360917

Product Details anti-IL20RA Antibody

Target: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Binding Specificity: Extracellular Domain

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL20RA antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects IL-20Ralpha.

Purification: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IL-20Ralpha extracellular domain.

Clone: 11C42

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL20RA

Target: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Alternative Name: IL20RA (IL20RA Products)

Synonyms: CRF2-8 antibody, IL-20R-alpha antibody, IL-20R1 antibody, IL-20RA antibody, E230031K19 antibody, interleukin 20 receptor subunit alpha antibody, interleukin 20 receptor, alpha antibody, IL20RA antibody, Il20ra antibody

Background: The receptor for interleukin 20 is a heterodimer of 2 orphan class II cytokine receptor subunits, IL20RA, also called ZCYTOR7, and IL20RB, also called DIRS1. Binding assays demonstrated that IL20 bound to BHK transfectants expressing both IL20RA and IL20RB, but not to untransfected cells nor to transfectants expressing either receptor subunit alone. Binding of (125)I labeled IL20 was eliminated in the presence of 100 fold excess of unlabeled IL20 but not in the presence of 100 fold excess of the unrelated cytokine, IL21. The binding data revealed 88,000 IL20 receptors per cell, with a binding affinity of approximately 1.5 nM. Both receptor subunits were expressed in skin and were dramatically upregulated in psoriatic skin.Synonyms: Cytokine receptor class-II member 8, Cytokine receptor family 2 member 8, IL-20R-alpha, IL-20R1, Interleukin-20 receptor alpha chain, ZCYTOR7

Gene ID: 237313

NCBI Accession: NP_766374

UniProt: Q6PHB0