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PIK3 gamma antibody (C-Term)

PIK3CG Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360452
  • Target See all PIK3 gamma (PIK3CG) Antibodies
    PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
    Binding Specificity
    • 16
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1073-1102, C-Term
    Reactivity
    • 115
    • 22
    • 4
    • 1
    Human
    Host
    • 107
    • 7
    • 1
    Rabbit
    Clonality
    • 108
    • 7
    Polyclonal
    Conjugate
    • 37
    • 10
    • 9
    • 9
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIK3 gamma antibody is un-conjugated
    Application
    • 95
    • 52
    • 39
    • 39
    • 31
    • 19
    • 14
    • 9
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PI3KCG.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1073~1102 amino acids from the C-terminal region of Human PI3KCG.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PIK3CG Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
    Alternative Name
    PIK3CG (PIK3CG Products)
    Synonyms
    PI3CG antibody, PI3K antibody, PI3Kgamma antibody, PIK3 antibody, Pi3k antibody, wu:fb15d07 antibody, zgc:77033 antibody, pi3k antibody, 5830428L06Rik antibody, p110gamma antibody, p120-PI3K antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma antibody, si:rp71-17i16.5 antibody, PIK3CG antibody, Pik3cg antibody, pik3cg antibody, si:rp71-17i16.5 antibody
    Background
    PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.Synonyms: 5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, Phosphatidylinositol-4, PtdIns-3-kinase subunit p110-gamma, p120-PI3K
    Gene ID
    5294, 9606
    UniProt
    P48736
    Pathways
    PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
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