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PKN3 antibody (C-Term)

PKN3 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360331
  • Target See all PKN3 Antibodies
    PKN3 (Protein Kinase N3 (PKN3))
    Binding Specificity
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 26
    • 22
    • 1
    Human
    Host
    • 37
    • 2
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKN3 antibody is un-conjugated
    Application
    • 29
    • 25
    • 9
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PKN beta.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PKN beta.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PKN3 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PKN3 (Protein Kinase N3 (PKN3))
    Alternative Name
    PKN3 (PKN3 Products)
    Synonyms
    prkcl2 antibody, wu:fb92a02 antibody, si:dkey-202g15.3 antibody, PKN3 antibody, RP11-545E17.1 antibody, AW209115 antibody, BC034126 antibody, LRRGT00147 antibody, protein kinase N3 antibody, pkn3 antibody, PKN3 antibody, Pkn3 antibody
    Background
    PKN3, a protein kinase C-related molecule, mediates malignant cell growth downstream of activated PI3K. PKN3 is required for invasive prostate cell growth as assessed by 3D cell culture assays and in an orthotopic mouse tumor model by inducible expression of short hairpin RNA (shRNA). PKN3 is regulated by PI3K at both the expression level and the catalytic activity level. Therefore, PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of PI3K.Synonyms: PKN beta, PKN-beta, PKNBETA, Protein-kinase C-related kinase 3, Serine/threonine-protein kinase N3
    Gene ID
    29941, 9606
    UniProt
    Q6P5Z2
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