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PAK4 antibody (N-Term)

PAK4 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN360324
  • Target See all PAK4 Antibodies
    PAK4 (P21-Activated Kinase 4 (PAK4))
    Binding Specificity
    • 13
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 85
    • 53
    • 35
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 79
    • 5
    • 1
    Rabbit
    Clonality
    • 80
    • 5
    Polyclonal
    Conjugate
    • 41
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAK4 antibody is un-conjugated
    Application
    • 69
    • 37
    • 20
    • 19
    • 10
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PAK4.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PAK4.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PAK4 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PAK4 (P21-Activated Kinase 4 (PAK4))
    Alternative Name
    PAK4 (PAK4 Products)
    Synonyms
    5730488L07Rik antibody, AW555722 antibody, mKIAA1142 antibody, im:5916170 antibody, wu:fd12b01 antibody, zgc:92014 antibody, p21 (RAC1) activated kinase 4 antibody, p21 protein (Cdc42/Rac)-activated kinase 4 antibody, PAK4 antibody, Pak4 antibody, pak4 antibody
    Background
    PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.Synonyms: KIAA1142, PAK 4, PAK-4, Serine/threonine-protein kinase PAK 4, p21-activated kinase 4
    Gene ID
    10298, 9606
    UniProt
    O96013
    Pathways
    RTK Signaling
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