PUM1 antibody (N-Term)

Catalog No. ABIN360015

Product Details anti-PUM1 Antibody

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUM1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Pumilio 1 (PUM1).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Protein A Chromatography followed by peptide affinity purification.

Immunogen: This antibody is generated from Rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Human PUM1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot 1/50approx. 1/100. Immunohistochemistry: 1/10approx. 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PUM1

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Alternative Name: Pumilio 1 / PUM1 (PUM1 Products)

Synonyms: fb96a03 antibody, pumilio1 antibody, si:ch211-285e16.1 antibody, wu:fb96a03 antibody, wu:fb96a08 antibody, zgc:63671 antibody, PUM1 antibody, DKFZp459K0627 antibody, AA517475 antibody, Pumm antibody, mKIAA0099 antibody, HSPUM antibody, PUMH antibody, PUMH1 antibody, PUML1 antibody, pumilio RNA-binding family member 1 antibody, pumilio RNA binding family member 1 antibody, pum1 antibody, PUM1 antibody, Pum1 antibody

Background: PUM1 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.Synonyms: HsPUM, KIAA0099, PUMH1, Pumilio homolog 1, Pumilio-1

Molecular Weight: 126473 Da

Gene ID: 9698

NCBI Accession: NP_055491

UniProt: Q14671