Cullin 5 antibody (C-Term)
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- Target See all Cullin 5 (CUL5) Antibodies
- Cullin 5 (CUL5)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cullin 5 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts with CUL5 (C-term).
- Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CUL5.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CUL5 Primary Antibody
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- Application Notes
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ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- Cullin 5 (CUL5)
- Alternative Name
- Cullin-5 (CUL5 Products)
- Synonyms
- cul5 antibody, wu:fd17d09 antibody, wu:fi20h12 antibody, xx:11fd17d09 antibody, zgc:66185 antibody, Xcullin5 antibody, CG1401 antibody, CUL5 antibody, Cul5 antibody, Cullin 5 antibody, Cullin5 antibody, Dmel\\CG1401 antibody, cul-5 antibody, vacm-1 antibody, vacm1 antibody, VACM-1 antibody, VACM1 antibody, 4921514I20Rik antibody, 8430423K24Rik antibody, AI852817 antibody, C030032G03Rik antibody, C330021I08Rik antibody, Cullin-5 antibody, cullin 5a antibody, cullin 5 L homeolog antibody, Cullin 5 antibody, cullin 5 antibody, Cullin-5 antibody, cul5a antibody, cul5.L antibody, Cul5 antibody, CUL5 antibody, cul5 antibody, cul-5 antibody
- Background
- CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein and may form a cell surface vasopressin receptor.Synonyms: CUL-5, CUL5, VACM-1, VACM1, Vasopressin-activated calcium-mobilizing receptor
- Molecular Weight
- 90955 Da predicted from amino acid sequence. Theoretical pI: 8.08
- Gene ID
- 8065, 9606
- UniProt
- Q93034
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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