PUM1 antibody (Tyr83)

Catalog No. ABIN359733

Product Details anti-PUM1 Antibody

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Binding Specificity: Tyr83

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PUM1.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y83 of human PUM1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PUM1

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Alternative Name: Pumilio 1 / PUM1 (PUM1 Products)

Background: PUM1 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.Synonyms: HsPUM, KIAA0099, PUMH1, Pumilio homolog 1, Pumilio-1

Gene ID: 9698, 9606

UniProt: Q14671