Myosin IC antibody (C-Term)

Catalog No. ABIN358975

Product Details anti-Myosin IC Antibody

Target: Myosin IC (MYO1C)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin IC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody reacts to Myosin 1C (MYO1C).

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MYO1C.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Myosin IC

Target: Myosin IC (MYO1C)

Alternative Name: Myosin-Ic (MYO1C Products)

Synonyms: MMI-beta antibody, MMIb antibody, NMI antibody, myr2 antibody, C80397 antibody, MYO1E antibody, mm1beta antibody, Myr2 antibody, mmib antibody, myo1c antibody, nm1 antibody, Myo1c antibody, Myosin-Ic antibody, MMI-beta-A antibody, MMIb-A antibody, DDBDRAFT_0202969 antibody, DDBDRAFT_0215355 antibody, DDB_0202969 antibody, DDB_0215355 antibody, 43CD antibody, CG2146 antibody, Didum antibody, DmV antibody, Dmel\CG2146 antibody, M5 antibody, MYOV antibody, Myo1C antibody, Myo5 antibody, MyoV antibody, MyoV43CD antibody, NEST:bs14c05 antibody, NMC7 antibody, dmM5 antibody, myoV antibody, soy antibody, myosin IC antibody, myosin 1C antibody, myosin IC L homeolog antibody, myosin Ic, paralog b antibody, myosin Ic, paralog a antibody, myosin IC S homeolog antibody, class I myosin antibody, dilute class unconventional myosin antibody, MYO1C antibody, Myo1c antibody, myo1c.L antibody, myo1cb antibody, myo1c antibody, myo1ca antibody, myo1c.S antibody, myoC antibody, didum antibody

Background: MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.Synonyms: MMI-beta, MMIb, MYO1C, Myosin I beta

Gene ID: 4641, 9606

UniProt: O00159

Pathways: Platelet-derived growth Factor Receptor Signaling