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SNURF antibody (Middle Region)

SNURF Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357983
  • Target See all SNURF Antibodies
    SNURF (SNRPN Upstream Reading Frame (SNURF))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human
    Host
    • 3
    • 2
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This SNURF antibody is un-conjugated
    Application
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SNURF (Center).
    Purification
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human SNURF.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SNURF Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    SNURF (SNRPN Upstream Reading Frame (SNURF))
    Alternative Name
    SNURF (SNURF Products)
    Synonyms
    2410045I01Rik antibody, Snrpn antibody, SNRPN upstream reading frame antibody, small nuclear ribonucleoprotein polypeptide N antibody, SNURF antibody, SNRPN antibody, Snurf antibody
    Background
    SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.Synonyms: SNRPN upstream reading frame protein
    Molecular Weight
    8412 Da (Theoretical pI: 10.58. WB band detected at approx 30kDa).
    Gene ID
    8926, 9606
    UniProt
    Q9Y675
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