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ICMT antibody (C-Term)

ICMT Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357792
  • Target See all ICMT Antibodies
    ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
    Binding Specificity
    • 15
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 39
    • 27
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 38
    • 1
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICMT antibody is un-conjugated
    Application
    • 32
    • 13
    • 13
    • 12
    • 4
    • 3
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects ICMT (C-term).
    Purification
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ICMT.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ICMT Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))
    Alternative Name
    ICMT / PCCMT (ICMT Products)
    Background
    This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing results in two transcript variants encoding different isoforms.Synonyms: Isoprenylcysteine carboxylmethyltransferase, PPMT, Prenylated protein carboxyl methyltransferase, Prenylcysteine carboxyl methyltransferase, Protein-S-isoprenylcysteine O-methyltransferase
    Molecular Weight
    31938 Da
    Gene ID
    23463, 9606
    UniProt
    O60725
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