ACSL6 antibody (Middle Region)

Catalog No. ABIN357782

Product Details anti-ACSL6 Antibody

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACSL6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to FACL6 (Center).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FACL6.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ACSL6

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Alternative Name: ACSL6 (ACSL6 Products)

Synonyms: ACS2 antibody, FACL6 antibody, LACS 6 antibody, LACS2 antibody, LACS5 antibody, ACSL6 antibody, MGC146229 antibody, Facl6 antibody, Lacsl antibody, A330035H04Rik antibody, AW050338 antibody, LACS antibody, mKIAA0837 antibody, wu:fa04h02 antibody, wu:fc05h07 antibody, acyl-CoA synthetase long chain family member 6 antibody, acyl-CoA synthetase long-chain family member 6 antibody, ACSL6 antibody, acsl6 antibody, Acsl6 antibody, LOAG_15918 antibody, LOC416323 antibody

Background: FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5,12)(q31,p13) that involves ETV6 and ACSL6.Synonyms: ACS2, FACL6, KIAA0837, LACS5, Long-chain acyl-CoA synthetase 6, Long-chain-fatty-acid--CoA ligase 6

Molecular Weight: 77680 Da

Gene ID: 23305, 5874

UniProt: Q9UKU0