ZMPSTE24 antibody (Middle Region)

Catalog No. ABIN357707

Product Details anti-ZMPSTE24 Antibody

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMPSTE24 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to ZMPSTE24 (Center).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZMPSTE24.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100-1/500. (See Ref.1)Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ZMPSTE24

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Alternative Name: ZMPSTE24 (Zmpste24 Products)

Synonyms: DDBDRAFT_0189115 antibody, DDBDRAFT_0237846 antibody, DDB_0189115 antibody, DDB_0237846 antibody, F2N1.21 antibody, F2N1_21 antibody, STE24 antibody, FACE-1 antibody, FACE1 antibody, HGPS antibody, PRO1 antibody, Ste24p antibody, A530043O15Rik antibody, D030046F19 antibody, Face-1 antibody, MADB antibody, fi45a02 antibody, wu:fi45a02 antibody, zgc:55655 antibody, zinc metallopeptidase STE24 antibody, zinc metallopeptidase STE24 L homeolog antibody, CAAX prenyl protease antibody, Peptidase family M48 family protein antibody, zinc metallopeptidase, STE24 antibody, zinc metallopeptidase, STE24 homolog antibody, ZMPSTE24 antibody, zmpste24.L antibody, zmpste24 antibody, ATSTE24 antibody, Zmpste24 antibody

Background: ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.Synonyms: CAAX prenyl protease 1 homolog, FACE-1, FACE1, Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, STE24, Zinc metalloproteinase Ste24 homolog

Molecular Weight: 54813 Da

Gene ID: 10269, 5874

UniProt: O75844