Epsin 2 antibody (N-Term)

Catalog No. ABIN357623

Product Details anti-Epsin 2 Antibody

Target: Epsin 2 (EPN2)

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epsin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to Epsin-2 (N-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Epsin2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Epsin 2

Target: Epsin 2 (EPN2)

Alternative Name: Epsin-2 (EPN2 Products)

Synonyms: CG13853 antibody, CG13854 antibody, CG31170 antibody, CG31285 antibody, CG42250 antibody, Dmel\\CG42250 antibody, Dmel_CG31170 antibody, Dmel_CG31285 antibody, Epsin antibody, LqfR antibody, XII-10 antibody, epsin antibody, epsin-like antibody, epsin02 antibody, epsinR antibody, l(3)03685 antibody, l(3)A9 antibody, l(3)SG62 antibody, l(3)XII-10 antibody, l(3)dsl-9 antibody, l(3)dsl9 antibody, EHB21 antibody, 9530051D10Rik antibody, AA536924 antibody, Ibp2 antibody, epsin-2 antibody, liquid facets-Related antibody, epsin 2 antibody, epsin-2 antibody, Epsin 2 antibody, epsin 2 S homeolog antibody, lqfR antibody, EPN2 antibody, EDI_326810 antibody, EDI_044850 antibody, Bm1_38210 antibody, EHI_104950 antibody, epn2 antibody, Epn2 antibody, epn2.S antibody

Background: Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.Synonyms: EPN2, EPS-15-interacting protein 2, KIAA1065

Molecular Weight: 68553 Da

Gene ID: 22905, 9606

UniProt: O95208

Pathways: EGFR Downregulation